[ Pobierz całość w formacie PDF ]
.Bioorg Med Chem Lett 20:726 729339.Suzuki G, Tsukamoto N, Fushiki H et al (2007) In vitro pharmacological characterization ofnovel isoxazolopyridone derivatives as allosteric metabotropic glutamate receptor 7 antago-nists.J Pharmacol Exp Ther 323:147 156340.Beart PM, O Shea RD (2007) Transporters for L-glutamate: an update on their molecularpharmacology and pathological involvement.Br J Pharmacol 150:5 17341.Moriyama Y, Omote H (2008) Vesicular glutamate transporter acts as a metabolic regulator.Biol Pharm Bull 31:1844 1846342.Takamori S (2006) VGLUTs:  exciting times for glutamatergic research? Neurosci Res55:343 351 146 E.Schaeffer and A.Duplantier343.Kashani A, Lepicard E, Poirel O et al (2008) Loss of VGLUT1 and VGLUT2 in theprefrontal cortex is correlated with cognitive decline in Alzheimer disease.NeurobiolAging 29:1619 1630344.Kashani A, Betancur C, Giros B et al (2007) Altered expression of vesicular glutamatetransporters VGLUT1 and VGLUT2 in Parkinson disease.Neurobiol Aging 28:568 578345.Hinoi E, Takarada T, Tsuchihashi Y et al (2005) Glutamate transporters as drug targets.CurrDrug Targets CNS Neurol Disord 4:211 220346.Shigeri Y, Seal RP, Shimamoto K (2004) Molecular pharmacology of glutamate transpor-ters, EAATs and VGLUTs.Brain Res Brain Res Rev 45:250 265347.Tzingounis AV, Wadiche JI (2007) Glutamate transporters: confining runaway excitation byshaping synaptic transmission.Nat Rev Neurosci 8:935 947348.Rose EM, Koo JC, Antflick JE et al (2009) Glutamate transporter coupling to Na, K-ATPase.J Neurosci 29:8143 8155349.Koch HP, Brown RL, Larsson HP (2007) The glutamate-activated anion conductance inexcitatory amino acid transporters is gated independently by the individual subunits.J Neurosci 27:2943 2947350.Teichberg VI, Cohen-Kashi-Malina K, Cooper I et al (2009) Homeostasis of glutamate in brainfluids: an accelerated brain-to-blood efflux of excess glutamate is produced by blood glutamatescavenging and offers protection from neuropathologies.Neuroscience 158:301 308351.Stafford MM, Brown MN, Mishra P et al (2010) Glutamate spillover augments GABAsynthesis and release from axodendritic synapses in rat hippocampus.Hippocampus20:134 144352.Maragakis NJ, Rothstein JD (2004) Glutamate transporters: animal models to neurologicdisease.Neurobiol Dis 15:461 473353.Sheldon AL, Robinson MB (2007) The role of glutamate transporters in neurodegenerativediseases and potential opportunities for intervention.Neurochem Int 51:333 355354.Su ZZ, Leszczyniecka M, Kang DC et al (2003) Insights into glutamate transport regulationin human astrocytes: cloning of the promoter for excitatory amino acid transporter2 (EAAT2).Proc Natl Acad Sci USA 100:1955 1960355.Yamashita A, Makita K, Kuroiwa T et al (2006) Glutamate transporters GLAST and EAAT4regulate postischemic Purkinje cell death: an in vivo study using a cardiac arrest model inmice lacking GLAST or EAAT4.Neurosci Res 55:264 270356.Tanaka K, Watase K, Manabe T et al (1997) Epilepsy and exacerbation of brain injury inmice lacking the glutamate transporter GLT-1.Science 276:1699 1702357.Lin CL, Bristol LA, Jin L et al (1998) Aberrant RNA processing in a neurodegenerativedisease: the cause for absent EAAT2, a glutamate transporter, in amyotrophic lateralsclerosis.Neuron 20:589 602358.Rothstein JD, Martin LJ, Kuncl RW (1992) Decreased glutamate transport by the brain andspinal cord in amyotrophic lateral sclerosis.N Engl J Med 326:1464 1468359.Honig LS, Chambliss DD, Bigio EH et al (2000) Glutamate transporter EAAT2 splicevariants occur not only in ALS, but also in AD and controls.Neurology 55:1082 1088360.Hoogland G, van Oort RJ, Proper EA et al (2004) Alternative splicing of glutamatetransporter EAAT2 RNA in neocortex and hippocampus of temporal lobe epilepsy patients.Epilepsy Res 59:75 82361.Jacob CP, Koutsilieri E, Bartl J et al (2007) Alterations in expression of glutamatergictransporters and receptors in sporadic Alzheimer s disease.J Alzheimers Dis 11:97 116362.Matos M, Augusto E, Oliveira CR et al (2008) Amyloid-beta peptide decreases glutamateuptake in cultured astrocytes: involvement of oxidative stress and mitogen-activated proteinkinase cascades.Neuroscience 156:898 910363.Vallejo-Illarramendi A, Domercq M, Perez-Cerda F et al (2006) Increased expression andfunction of glutamate transporters in multiple sclerosis.Neurobiol Dis 21:154 164364 [ Pobierz całość w formacie PDF ]

  • zanotowane.pl
  • doc.pisz.pl
  • pdf.pisz.pl
  • fisis2.htw.pl
  • Copyright © 2016 (...) chciaÅ‚bym posiadać wszystkie oczy na ziemi, żeby patrzeć na Ciebie.
    Design: Solitaire